- Dimpho Ditsebe
- Oct 6
- 4 min read
Midlife can feel like a big turning point in a woman’s life. Hormones begin to shift and with that comes changes in your body, your mood, and even your overall health. The good news is that with the right support and lifestyle choices, you can manage this phase confidently and stay healthy and vibrant.
What happens to hormones in midlife
From the age of about 40 onwards, sometimes can happen earlier, many women begin to notice the effects of changing hormones. As the ovaries produce less oestrogen and progesterone, you may experience:
Hot flushes and night sweats
Mood changes and irritability
Irregular or missed periods
Weight gain or slower metabolism
These changes are natural, but they can affect more than just day-to-day comfort. They also influence bone health, heart health and emotional well-being.
Learn more about how women’s bodies change during this stage on our dedicated page:

Practical tips for managing hormonal changes in women
At Myclinic, we believe in a team-based approach. Here’s how different aspects of midlife care can be supported by both healthy habits and professional help:
1. Eat well and nourish your body, with support from our Dietician
A diet rich in vegetables, fruit, lean proteins and wholegrains helps balance hormones and keeps your bones and heart healthy. Foods high in calcium and vitamin D are especially important for preventing osteoporosis.
Our dieticians Sinhle available in Soweto and Phamela available in Braamfontein can help you create a midlife-friendly meal plan that suits your lifestyle and goals.
2. Keep Moving, with guidance from our Physiotherapist
Exercise is one of the most powerful tools during midlife. It helps manage weight, boosts mood, strengthens bones, and protects heart health. Aim for at least 150 minutes of activity a week, mixing cardio (walking, cycling) with strength training.
Our physiotherapists Vuyisile and Ledile can design safe, personalised exercises, especially if you’re dealing with joint pain, stiffness, or injury.
3. Manage Stress and Sleep, with our Psychologist
Hormone changes can make stress feel more intense and can disrupt sleep. Practices like mindfulness, deep breathing, or yoga are useful, but sometimes you may need extra support.
Our psychologist, Buyisile, helps patients manage stress, anxiety, and emotional changes during midlife, supporting both mental and emotional resilience.
4. Medical treatments and check-ups
Some women benefit from medical treatments such as Hormone Replacement Therapy (HRT) to manage severe menopausal symptoms. These options should always be discussed with a doctor to ensure they’re safe and suitable for your personal health history.
Why regular screening matters: Midlife is also a key time to prioritise preventative health checks. As oestrogen levels fall, risks of certain conditions, including osteoporosis, heart disease and some cancers, increase. Regular screenings can detect issues early, when they’re easiest to treat.
At Myclinic, we encourage women to stay proactive about:
Breast health: Annual clinical breast exams and mammograms (from age 40, or earlier if you have a family history).
Cervical health: Pap smears every 3 years, or as advised by your clinician.
Colon health: Colon cancer screening from age 45 onwards.
Skin checks: Early detection of melanoma or sun-related changes is vital.
Our Myclinic clinicians and doctors provide guidance on which screenings are right for you and help coordinate tests with our trusted partners such as Toga Laboratories for pathology.
Whole-person care: If results reveal risk factors, our multidisciplinary team work together to support lifestyle changes, nutrition plans, exercise routines and emotional well-being through any diagnosis or recovery phase.
5. Hydration and skin care
As oestrogen levels drop during midlife, skin often becomes drier, thinner and more sensitive. You might notice that your usual skincare routine no longer works quite as well. This is because hormonal changes reduce collagen production and slow down the skin’s natural ability to retain moisture.
Hydration inside and out: Drinking enough water helps maintain skin elasticity and flush out toxins. Aim for about 6–8 glasses a day and add water-rich foods like cucumbers, berries, and citrus fruits to your diet. Limiting caffeine and alcohol, both of which can dehydrate the skin, also helps maintain a healthy glow.
Gentle, nourishing skincare: Switch to fragrance-free moisturisers and mild cleansers that protect the skin barrier. Ingredients such as hyaluronic acid, ceramides and vitamin E can help lock in moisture and soothe irritation. Don’t forget daily sunscreen, as skin becomes more prone to sun damage during this stage.

Can hormonal imbalance cause fever?
Hormonal imbalances can cause a variety of symptoms, but fever is not commonly one of them. Fever typically indicates an infection or inflammation rather than a direct result of hormonal fluctuations. However, some women may experience hot flashes and night sweats during menopause, which can feel like sudden warmth or chills but are not true fevers.
If a woman experiences a persistent fever, it is important to seek medical advice to rule out infections or other underlying conditions. Hormonal changes can sometimes affect the immune system, but fever should not be attributed solely to hormonal imbalance without proper evaluation.
Understanding the difference between menopausal symptoms and signs of illness is crucial for appropriate care.

Lifestyle adjustments to support hormonal health
Beyond diet and exercise, several lifestyle changes can help manage midlife hormonal changes effectively:
Quit Smoking: Smoking can exacerbate menopausal symptoms and increase the risk of heart disease and osteoporosis.
Limit Alcohol: Excessive alcohol intake can disrupt hormone levels and worsen symptoms like hot flashes.
Maintain a Healthy Weight: Excess body fat can produce estrogen, which may complicate hormonal balance.
Stay Socially Connected: Emotional support from friends and family can improve mental health during this transition.
Regular Health Screenings: Bone density tests, cholesterol checks and blood pressure monitoring are important during midlife.
Incorporating these habits can improve quality of life and reduce the impact of hormonal changes.
Embracing midlife with confidence and care
Midlife is a natural stage of life and it doesn’t have to reduce your quality of life. With healthy habits, professional guidance and support from our Allied healthcare team, you can take control of your health and thrive.
For men interested in how midlife affects them, visit our page:
At Myclinic, we’re here to walk this journey with you, whether through nutritional guidance, physiotherapy, psychological support or pathology tests. Together, we can make midlife a season of strength and vitality.



















